Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | ranked_basal_vs_classical |
| Phenotype | NoPhenotypeAvailable |
| Upregulated in class | na_neg |
| GeneSet | ESTROGEN SYNTHESIS AND METABOLISM%WIKIPATHWAYS_20260410%WP5276%HOMO SAPIENS |
| Enrichment Score (ES) | -0.85529995 |
| Normalized Enrichment Score (NES) | -1.8855408 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.010700012 |
| FWER p-Value | 0.252 |
| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | UGT1A10 | 2892 | 1.329 | -0.1393 | No |
| 2 | CYP1B1 | 5795 | 0.396 | -0.2941 | No |
| 3 | UGT1A8 | 7288 | 0.171 | -0.3742 | No |
| 4 | HSD17B1 | 10134 | -0.130 | -0.5300 | No |
| 5 | SULT1E1 | 11128 | -0.264 | -0.5809 | No |
| 6 | HSD17B10 | 12727 | -0.577 | -0.6604 | No |
| 7 | HSD17B4 | 16222 | -2.325 | -0.8172 | Yes |
| 8 | HSD17B3 | 16909 | -3.478 | -0.7997 | Yes |
| 9 | HSD17B7 | 17091 | -3.884 | -0.7477 | Yes |
| 10 | CYP2C8 | 17160 | -4.113 | -0.6857 | Yes |
| 11 | UGT2B7 | 17333 | -4.728 | -0.6197 | Yes |
| 12 | CYP2C19 | 17507 | -5.600 | -0.5398 | Yes |
| 13 | CYP2C9 | 17616 | -6.352 | -0.4443 | Yes |
| 14 | CYP3A4 | 17811 | -8.382 | -0.3211 | Yes |
| 15 | HSD17B2 | 17870 | -9.595 | -0.1710 | Yes |
| 16 | CYP3A7 | 17937 | -11.246 | 0.0051 | Yes |
